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Chemo Round 2: similar overall impact, but the mix of side effects is different each time. Weird!

20 Mar 2026 5 month(s) ago 2 Comments

Key Points:

  • Round 2 has been similar overall to Round 1 – ie nothing debilitating, life-changing, or permanent - and back to normal day-to-day life by about day 7 (ie 4 days recovery after 3 days of chemo).
  • Still about a dozen side effects, but the mix is different each time!
  • I put my chemo side effects into 5 columns: – ‘Gone’, ‘Less’, ‘Same’, ‘Worse’, and ‘New’.
  • The ‘Worse’ and ‘New’ side effects are the ones to watch because chemo is cumulative - the body doesn’t ‘get used it’. It builds up over time, and side effects can become permanent.
  • So far, the whole cancer surgery/chemo journey has been much better than I had been expecting. Very lucky that I have been having a pretty good run compared to many or most chemo experiences.
  • It is still early days yet, but so far so good!
  • Once again a huge thank you for all the kind words of support and encouragement I have received from near and far. Very much appreciated!

 

This is a quick progress report on my cancer journey.

Recapping the story so far

In early December 2025 I received a positive bowel cancer screen out of the blue (ie no symptoms or any other indications); spent the rest of December doing tests, scans, colonoscopy, etc; had surgery in early January 2026 to remove left side of large intestine, plus appendix, lymph nodes, and surrounding tissues.

Post-op biopsies and tests confirmed ‘stage 3’ cancer, meaning it is at ‘advanced’ stage but ‘localised’ to the surrounding areas. There is a good chance the surgeon got all the cancer out in surgery, but still a chance of more cancer in there somewhere. Hence the program of 12 fortnights of chemotherapy starting late February 2026.

My story on Round 1 outlined my side effects – physical, mental, and weight. There were about a dozen side effects for me. Good news is that so far, none have been debilitating or life-changing or permanent, so I have been very lucky so far.

This first round of chemo had an additional complication – the catheter port insertion surgery was the day before chemo started, so that involved a little pain and awkwardness. More nuisance than problem.

Different mix of side effects each time

Overall, Round 2 has been similar to Round 1 – back to normal day-to-day life by about day 7 (ie 4 days recovery after 3 days of chemo), with minimal lingering side effects.

However, although the side effects in Round 2 were somewhat similar to Round 1, the big surprise for me was that the mix of side effects different.

I put my side effects of chemo into 5 columns: – ‘Gone’, ‘Less’, ‘Same’, ‘Worse’, and ‘New’. There are some in each column.

 

I think most of the side effects I had in Round 1 but were ‘Gone’ in Round 2 were due to the fact that in the first round I was still recovering from the catheter port insertion surgery the day before, and still recovering from the colorectal surgery in January.

The ‘Worse’ and ‘New’ side effects are the ones to watch because chemo is cumulative - the body doesn’t ‘get used it’. It builds up over time, and side effects can become permanent.

The main point of the table is not the actual side effects themselves (because every chemo experience is different for each person) but the fact that the mix of side effects has been different from round to round – for me anyway.

One important change I have noticed since the surgery and start of chemo is that I am now much more aware of what is going on in my body. It’s not like I can actually ‘feel’ each organ because most of the internal organs have no nerve endings. But I certainly have a much better sense of changes – physical and mental.

Overall

It’s a whole new experience for me, so I went into chemo prepared for the worst but hoping for the best. It has certainly been a lot less disruptive than I had been expecting. Maybe I have been lucky. Who knows?

It is still early days yet, but so far so good!

Please note that these are just my personal observations and experiences from a sample of one. Every patient is different, every cancer is different, and every chemo program is different. I have talked to several friends and relatives who have gone through their own cancer journeys and their ranges of experiences and side effects have been many and varied.

Finally - a huge thank you once again for all the kind words of support and encouragement I have received from near and far. Very much appreciated!

‘Till next time – safe investing and stay healthy!

See also:

 

  • My Life in Weeks: 83% done, but there’s a nasty new twist this year. “Life’s like a box of chocolates. . .” (4-Jan-2026)

 

 

 

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2 Comments

Existing Comments

Hey Gary - thanks for your support and encouragement! - I've been pretty lucky so far. Hopefully will kill things and be ok at the end!
cheers
ao

ashley owen
March 21, 2026

Fascinating description of your journey and fight to beat or subdue the Big C.Hang in...my thoughts and best wishes are with you.You sound positive which I understand is almost a win.Fight the bastard....

Gary Buchanan
March 21, 2026

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